Comprehensive Integration of Single-Cell Transcriptional Profiling Reveals the Heterogeneities of Non-cardiomyocytes in Healthy and Ischemic Hearts

Comprehensive Integration of Single-Cell Transcriptional Profiling Reveals the Heterogeneities of Non-cardiomyocytes in Healthy and Ischemic Hearts

Advances in single-cell RNA sequencing (scRNA-seq) technology have recently shed light on the molecular mechanisms of the spatial and temporal changes of thousands of cells simultaneously under homeostatic and ischemic conditions. The aim of this study is to investigate whether it is possible to int...

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Bibliographic Details
Main Authors: Lingfang Zhuang, Lin Lu, Ruiyan Zhang, Kang Chen, Xiaoxiang Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
myocardial infarction
single-cell RNA sequencing
immune system
non-cardiomyocytes
macrophages
Ddah1
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2020.615161/full

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