Conserved phosphoryl transfer mechanisms within kinase families and the role of the C8 proton of ATP in the activation of phosphoryl transfer

<p>Abstract</p> <p>Background</p> <p>The kinome is made up of a large number of functionally diverse enzymes, with the classification indicating very little about the extent of the conserved kinetic mechanisms associated with phosphoryl transfer. It has been demonstrate...

Full description

Bibliographic Details
Main Authors: Kenyon Colin P, Roth Robyn L, van der Westhuyzen Chris W, Parkinson Christopher J
Format: Article
Language:English
Published: BMC 2012-03-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/5/131