Obstructive sleep apnea syndrome (OSAS) related hypertension: A review of pathophysiology and potential therapeutic approaches

• Main Author: Ayşegül Navdar
• Format: Article
• Language: English
• Published: Journal of Surgery and Medicine 2020-05-01
• Series: Journal of Surgery and Medicine
• Subjects: obstructive sleep apnea syndrome; hypertension; cpap; upper airway surgery; obstruktif uyku apne sendromu; hipertansiyon; pap; üst havayolu cerrahisi
• Online Access: https://dergipark.org.tr/en/pub/josam/issue/54145/727915

Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder related with cardiovascular diseases, including hypertension. There are lots of evidence supporting the relationship between OSAS and hypertension, modulated by multiple factors, but the exact mechanisms underlying this complex cause and effect relationship remain unclear. The alternating pattern of OSAS-related hypertension is closely related with target organ damage, especially in the heart and brain. In this review, the etiological factors, clinical types, probable pathophysiologic mechanisms, diagnostic methods, and current therapeutic approaches to OSAS-related hypertension is discussed in the light of current literature.