TLR4 and Insulin Resistance
Chronic inflammation is a key feature of insulin resistance and obesity. Toll-Like Receptor 4 (TLR4), involved in modulating innate immunity, is an important mediator of insulin resistance and its comorbidities. TLR4 contributes to the development of insulin resistance and inflammation through its...
Main Authors: | Jane J. Kim, Dorothy D. Sears |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2010-01-01
|
Series: | Gastroenterology Research and Practice |
Online Access: | http://dx.doi.org/10.1155/2010/212563 |
Similar Items
-
Pharmacological TLR4 Inhibition Protects against Acute and Chronic Fat-Induced Insulin Resistance in Rats.
by: Ning Zhang, et al.
Published: (2015-01-01) -
TLR4 Expression by Liver Resident Cells Mediates the Development of Glucose Intolerance and Insulin Resistance in Experimental Periodontitis.
by: Vladimir Ilievski, et al.
Published: (2015-01-01) -
Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice.
by: Andréa M Caricilli, et al.
Published: (2011-12-01) -
Molecular Mechanisms Underlying Obesity-Induced Hypothalamic Inflammation and Insulin Resistance: Pivotal Role of Resistin/TLR4 Pathways
by: Yacir Benomar, et al.
Published: (2019-03-01) -
Correlation of methylation of toll-like receptor 4 (TLR4) and interleukin-6 (IL6) promoter with insulin resistance in obese adolescents
by: Ratih Feraritra Danu Atmaja, et al.
Published: (2016-06-01)