Heat Killed Attenuated Leishmania Induces Apoptosis of HepG2 Cells Through ROS Mediated p53 Dependent Mitochondrial Pathway

Heat Killed Attenuated Leishmania Induces Apoptosis of HepG2 Cells Through ROS Mediated p53 Dependent Mitochondrial Pathway

Background/Aims: Cytotoxic effect of attenuated Leishmania on liver cancer cells by inducing ROS generation. Methods: Spectrophotometric study to analyze cell death and levels of different active caspases. Flow cytometric study was done to analyze apoptosis induction and ROS generation and levels of...

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Bibliographic Details
Main Authors: Dipayan Bose, Somenath Banerjee, Subhadip Das, Nabanita Chatterjee, Krishna Das Saha
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Leishmania donovani
UR6
HepG2
p53
ROS
Gp91
Online Access:http://www.karger.com/Article/FullText/443125

Internet

http://www.karger.com/Article/FullText/443125

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