Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection.

Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection.

Schistosomiasis is a chronic parasitic disease caused by sexually dimorphic blood flukes of the genus Schistosoma. Praziquantel (PZQ) is the only drug widely available to treat the disease but does not kill juvenile parasites. Here we report the use of next generation sequencing to study the transcr...

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Bibliographic Details
Main Authors: Melissa C Sanchez, Katina V Krasnec, Amalia S Parra, Christian von Cabanlong, Geoffrey N Gobert, Boris Umylny, Pauline M Cupit, Charles Cunningham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5501684?pdf=render

Internet

http://europepmc.org/articles/PMC5501684?pdf=render

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