Induction therapy in newly diagnosed multiple myeloma: Current research scenario and questions for the future

The outcomes of patients with newly diagnosed multiple myeloma (NDMM) have substantially improved over the last decade. Besides improved staging, diagnostic and prognostic tools leading to better risk-stratified approaches, a major contributing factor has been better induction regimens. The major em...

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Bibliographic Details
Main Authors: Bhausaheb Bagal, Avinash Bonda
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Cancer Research, Statistics, and Treatment
Subjects:
Online Access:http://www.crstonline.com/article.asp?issn=2590-3233;year=2019;volume=2;issue=1;spage=76;epage=82;aulast=Bagal
Description
Summary:The outcomes of patients with newly diagnosed multiple myeloma (NDMM) have substantially improved over the last decade. Besides improved staging, diagnostic and prognostic tools leading to better risk-stratified approaches, a major contributing factor has been better induction regimens. The major emphasis of the current clinical research is on the development of induction regimens capable of producing a deep and durable remission as measured by minimal residual disease negativity, which correlates with a better overall survival. This review explores the current changing landscape of induction therapy in NDMM and discusses implications for the current clinical practice.
ISSN:2590-3233
2590-3225