Lassa Virus Targeting of Anterior Uvea and Endothelium of Cornea and Conjunctiva in Eye of Guinea Pig Model

Lassa Virus Targeting of Anterior Uvea and Endothelium of Cornea and Conjunctiva in Eye of Guinea Pig Model

Lassa virus (LASV), a hemorrhagic fever virus endemic to West Africa, causes conjunctivitis in patients with acute disease. To examine ocular manifestations of LASV, we histologically examined eyes from infected guinea pigs. In fatal disease, LASV immunostaining was most prominent in the anterior uv...

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Bibliographic Details
Main Authors: Joy M. Gary, Stephen R. Welch, Jana M. Ritter, JoAnn Coleman-McCray, Thanhthao Huynh, Markus H. Kainulainen, Brigid C. Bollweg, Vaunita Parihar, Stuart T. Nichol, Sherif R. Zaki, Christina F. Spiropoulou, Jessica R. Spengler
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2019-05-01
Series:Emerging Infectious Diseases
Subjects:
Lassa fever
Lassa virus
viral hemorrhagic fever
ocular
eye
anterior uvea
Online Access:https://wwwnc.cdc.gov/eid/article/25/5/18-1254_article

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