Diacylglycerol is the preferred substrate in high density lipoproteins for human hepatic lipase

Diacylglycerol is the preferred substrate in high density lipoproteins for human hepatic lipase

The hydrolysis of HDL phospholipids (PL) and glycerides by hepatic lipase (HL) has been investigated in native and reconstituted HDL particles (Lp2A-I). Fasting, normolipidemic HDL exhibit total lipid hydrolytic rates of between 10 and 36 nM FA/h per microM PL. Of the total fatty acids liberated wit...

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Bibliographic Details
Main Authors: C R Coffill, T A Ramsamy, D M Hutt, J R Schultz, D L Sparks
Format: Article
Language:English
Published: Elsevier 1997-11-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520349361

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