SIMULTANEOUS INFECTION WITH DENGUE 1 AND 2 IN A BRAZILIAN PATIENT

• Main Authors: ROCCO Iray Maria, BARBOSA Maria Luisa, KANOMATA Emilia Hiromi Nakaya
• Format: Article
• Language: English
• Published: Universidade de São Paulo 1998-01-01
• Series: Revista do Instituto de Medicina Tropical de São Paulo
• Subjects: Dengue; Simultaneous infection; Virus isolation; PCR
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651998000300004

Dengue outbreaks have occurred in several Brazilian States since 1986 involving serotypes 1 (DEN-1) and 2 (DEN-2). In view of the few cases of double infection documented in the literature, we report here a case of simultaneous infection with DEN-1 and DEN-2 in a patient residing in the municipality of Miranda, State of Mato Grosso do Sul, Western region of Brazil. DEN-1 was introduced in this State in 1989 and DEN-2 in 1996, both of them circulating in some municipalities. This double infection was identified by virus isolation and by indirect immunofluorescence using monoclonal antibodies and confirmed by the polymerase chain reaction (PCR). This is the first documented case of simultaneous infection with serotypes DEN-1 and DEN-2 in Brazil.