Low C3 Serum Levels Predict Severe Forms of STEC-HUS With Neurologic Involvement

Low C3 Serum Levels Predict Severe Forms of STEC-HUS With Neurologic Involvement

Background: The correlation between the severity of hemolytic uremic syndrome related to Shiga toxin–producing Escherichia coli (STEC-HUS) and involvement of the complement system has been examined in a small number of studies, with conflicting results. In the present study, we investigated whether...

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Main Authors: Giuseppe Stefano Netti, Luisa Santangelo, Leonardo Paulucci, Giovanni Piscopo, Diletta D. Torres, Vincenza Carbone, Paolo Giordano, Federica Spadaccino, Giuseppe Castellano, Giovanni Stallone, Loreto Gesualdo, Maria Chironna, Elena Ranieri, Mario Giordano
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Medicine
Subjects:
hemolytic uremic syndrome
Shiga-toxin E. coli
neurologic involvement
complement system
C3 serum levels
Eculizumab
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00357/full

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