Long-Term Severe In Vitro Hypoxia Exposure Enhances the Vascularization Potential of Human Adipose Tissue-Derived Stromal Vascular Fraction Cell Engineered Tissues

Long-Term Severe In Vitro Hypoxia Exposure Enhances the Vascularization Potential of Human Adipose Tissue-Derived Stromal Vascular Fraction Cell Engineered Tissues

The therapeutic potential of mesenchymal stromal/stem cells (MSC) for treating cardiac ischemia strongly depends on their paracrine-mediated effects and their engraftment capacity in a hostile environment such as the infarcted myocardium. Adipose tissue-derived stromal vascular fraction (SVF) cells...

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Bibliographic Details
Main Authors: Myroslava Mytsyk, Giulia Cerino, Gregory Reid, Laia Gili Sole, Friedrich S. Eckstein, David Santer, Anna Marsano
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
hypoxic culture
stromal vascular fraction cells
engineered tissues
in vivo angiogenesis
Online Access:https://www.mdpi.com/1422-0067/22/15/7920

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