Determination of TREC and KREC reference intervals for immunodeficiency newborn screening in the Russian Federation

Determination of TREC and KREC reference intervals for immunodeficiency newborn screening in the Russian Federation

In this work we used a reference population of newborns and sampled dried blood spots on Guthrie cards of 2,739 individual samples to determine the reference interval of TRECs and KRECs values in order to diagnose primary immunodeficiency due to neonatal screening. The median of absolute TRECs and K...

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Bibliographic Details
Main Authors: Maria Alexandrovna Gordukova, Ilya Anatolievich Korsunsky, Yulia Vladimirovna Chursinova, Maria Mikhailovna Byakhova, Igor Petrovich Oskorbin, Andrey Petrovich Prodeus, Maxim Leonidovich Filipenko
Format: Article
Language:Russian
Published: SPb RAACI 2019-03-01
Series:Medicinskaâ Immunologiâ
Subjects:
Primary immunodeficiency (PID)
T-cells
B-cells, screening
TREC
KREC
newborn
reference intervals
Online Access:https://www.mimmun.ru/mimmun/article/view/1719

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