The Relevance of the MCP Risk Polymorphism to the Outcome of aHUS Associated With C3 Mutations. A Case Report

The Relevance of the MCP Risk Polymorphism to the Outcome of aHUS Associated With C3 Mutations. A Case Report

Thrombotic microangiopathy (TMA) has different etiological causes, and not all of them are well understood. In atypical hemolytic uremic syndrome (aHUS), the TMA is caused by the complement dysregulation associated with pathogenic mutations in complement components and its regulators. Here, we descr...

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Bibliographic Details
Main Authors: Javier Lumbreras, Marta Subias, Natalia Espinosa, Juana María Ferrer, Emilia Arjona, Santiago Rodríguez de Córdoba
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
C3
MCP risk polymorphism
atypical hemolytic uremic syndrome
de novo mutation
case report
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01348/full

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