Development of a Platform for Noncovalent Coupling of Full Antigens to Tobacco Etch Virus-Like Particles by Means of Coiled-Coil Oligomerization Motifs

Development of a Platform for Noncovalent Coupling of Full Antigens to Tobacco Etch Virus-Like Particles by Means of Coiled-Coil Oligomerization Motifs

Virus-like particles are excellent inducers of the adaptive immune response of humans and are presently being used as scaffolds for the presentation of foreign peptides and antigens derived from infectious microorganisms for subunit vaccine development. The most common approaches for peptide and ant...

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Bibliographic Details
Main Authors: Lorena Zapata-Cuellar, Jorge Gaona-Bernal, Carlos Alberto Manuel-Cabrera, Moisés Martínez-Velázquez, Carla Sánchez-Hernández, Darwin Elizondo-Quiroga, Tanya Amanda Camacho-Villegas, Abel Gutiérrez-Ortega
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
subunit vaccines
antigen carrier
virus-like particles
noncovalent coupling
heterodimerization motifs
antigen uptake
Online Access:https://www.mdpi.com/1420-3049/26/15/4436

Internet

https://www.mdpi.com/1420-3049/26/15/4436

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