Towards Antiviral shRNAs Based on the AgoshRNA Design.

Towards Antiviral shRNAs Based on the AgoshRNA Design.

RNA interference (RNAi) can be induced by intracellular expression of a short hairpin RNA (shRNA). Processing of the shRNA requires the RNaseIII-like Dicer enzyme to remove the loop and to release the biologically active small interfering RNA (siRNA). Dicer is also involved in microRNA (miRNA) proce...

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Bibliographic Details
Main Authors: Ying Poi Liu, Margarete Karg, Elena Herrera-Carrillo, Ben Berkhout
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4472832?pdf=render

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