Data on macrophage mediated muscle transfection upon delivery of naked plasmid DNA with block copolymers

The data contains 14 figures supporting the research article “Horizontal gene transfer from macrophages to ischemic muscles upon delivery of naked DNA with Pluronic block copolymers” [1]. The data explains the surgical procedure and histological characterization of Murine Hind Limb Ischemia. The dat...

Full description

Bibliographic Details
Main Authors:	Vivek Mahajan, Zagit Gaymalov, Daria Alakhova, Richa Gupta, Irving H. Zucker, Alexander V. Kabanov
Format:	Article
Language:	English
Published:	Elsevier 2016-06-01
Series:	Data in Brief
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352340916301950

id	doaj-273a1a66799641a38417a89c7495316f
record_format	Article
spelling	doaj-273a1a66799641a38417a89c7495316f2020-11-25T02:11:36ZengElsevierData in Brief2352-34092016-06-01712691282Data on macrophage mediated muscle transfection upon delivery of naked plasmid DNA with block copolymersVivek Mahajan0Zagit Gaymalov1Daria Alakhova2Richa Gupta3Irving H. Zucker4Alexander V. Kabanov5Division of Molecular Pharmaceutics, Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, NC 27599, USA; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5850, USADivision of Molecular Pharmaceutics, Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, NC 27599, USA; Department of Pharmaceutical Sciences and Center for Drug Delivery and Nanomedicine, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198-5850, USADivision of Molecular Pharmaceutics, Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, NC 27599, USADivision of Molecular Pharmaceutics, Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, NC 27599, USADepartment of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE 68198-5850, USADivision of Molecular Pharmaceutics, Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, NC 27599, USA; Department of Pharmaceutical Sciences and Center for Drug Delivery and Nanomedicine, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198-5850, USA; Laboratory of Chemical Design of Bionanomaterials, Faculty of Chemistry, M.V. Lomonosov Moscow State University, 119899 Moscow, Russia; Correspondence to: Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, NC 27599-7362, USA. Tel.: +1 919 9660327 (office), +1 919 9664453 (lab); fax: +1 919 9666927.The data contains 14 figures supporting the research article “Horizontal gene transfer from macrophages to ischemic muscles upon delivery of naked DNA with Pluronic block copolymers” [1]. The data explains the surgical procedure and histological characterization of Murine Hind Limb Ischemia. The data also shows the kinetics of luciferase gene expression, spread of GFP expression through muscle and the colocalization of GFP with cellular markers in ischemic muscles injected with pDNA alone or pDNA/Pluronic. Finally the data shows the effect of Pluronic Block Copolymer to enhance total gene expression (cmv-promoter driven luciferase gene) in coculture of DNA transfected MØs with muscle cells.http://www.sciencedirect.com/science/article/pii/S2352340916301950
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Vivek Mahajan Zagit Gaymalov Daria Alakhova Richa Gupta Irving H. Zucker Alexander V. Kabanov
spellingShingle	Vivek Mahajan Zagit Gaymalov Daria Alakhova Richa Gupta Irving H. Zucker Alexander V. Kabanov Data on macrophage mediated muscle transfection upon delivery of naked plasmid DNA with block copolymers Data in Brief
author_facet	Vivek Mahajan Zagit Gaymalov Daria Alakhova Richa Gupta Irving H. Zucker Alexander V. Kabanov
author_sort	Vivek Mahajan
title	Data on macrophage mediated muscle transfection upon delivery of naked plasmid DNA with block copolymers
title_short	Data on macrophage mediated muscle transfection upon delivery of naked plasmid DNA with block copolymers
title_full	Data on macrophage mediated muscle transfection upon delivery of naked plasmid DNA with block copolymers
title_fullStr	Data on macrophage mediated muscle transfection upon delivery of naked plasmid DNA with block copolymers
title_full_unstemmed	Data on macrophage mediated muscle transfection upon delivery of naked plasmid DNA with block copolymers
title_sort	data on macrophage mediated muscle transfection upon delivery of naked plasmid dna with block copolymers
publisher	Elsevier
series	Data in Brief
issn	2352-3409
publishDate	2016-06-01
description	The data contains 14 figures supporting the research article “Horizontal gene transfer from macrophages to ischemic muscles upon delivery of naked DNA with Pluronic block copolymers” [1]. The data explains the surgical procedure and histological characterization of Murine Hind Limb Ischemia. The data also shows the kinetics of luciferase gene expression, spread of GFP expression through muscle and the colocalization of GFP with cellular markers in ischemic muscles injected with pDNA alone or pDNA/Pluronic. Finally the data shows the effect of Pluronic Block Copolymer to enhance total gene expression (cmv-promoter driven luciferase gene) in coculture of DNA transfected MØs with muscle cells.
url	http://www.sciencedirect.com/science/article/pii/S2352340916301950
work_keys_str_mv	AT vivekmahajan dataonmacrophagemediatedmuscletransfectionupondeliveryofnakedplasmiddnawithblockcopolymers AT zagitgaymalov dataonmacrophagemediatedmuscletransfectionupondeliveryofnakedplasmiddnawithblockcopolymers AT dariaalakhova dataonmacrophagemediatedmuscletransfectionupondeliveryofnakedplasmiddnawithblockcopolymers AT richagupta dataonmacrophagemediatedmuscletransfectionupondeliveryofnakedplasmiddnawithblockcopolymers AT irvinghzucker dataonmacrophagemediatedmuscletransfectionupondeliveryofnakedplasmiddnawithblockcopolymers AT alexandervkabanov dataonmacrophagemediatedmuscletransfectionupondeliveryofnakedplasmiddnawithblockcopolymers
_version_	1724913956872519680

Data on macrophage mediated muscle transfection upon delivery of naked plasmid DNA with block copolymers

Similar Items