RHOA and mDia1 promotes apoptosis of breast cancer cells via a high dose of doxorubicin treatment

Transforming RhoA proteins (RHOA) and their downstream Diaphanous homolog 1 proteins (DIAPH1) or mDia1 participate in the regulation of actin cytoskeleton which plays critical role in cells, i.e., morphologic changes and apoptosis.

Bibliographic Details
Main Authors:	Bober Peter, Alexovič Michal, Tomková Zuzana, Kilík Róbert, Sabo Ján
Format:	Article
Language:	English
Published:	De Gruyter 2019-12-01
Series:	Open Life Sciences
Subjects:	transforming rhoa protein diaphanous homolog 1 protein actin cytoskeleton stress fibre
Online Access:	https://doi.org/10.1515/biol-2019-0070

id	doaj-2735e8dd422743b680133635f01f65d5
record_format	Article
spelling	doaj-2735e8dd422743b680133635f01f65d52021-09-05T20:42:24ZengDe GruyterOpen Life Sciences2391-54122019-12-0114161962710.1515/biol-2019-0070biol-2019-0070RHOA and mDia1 promotes apoptosis of breast cancer cells via a high dose of doxorubicin treatmentBober Peter0Alexovič Michal1Tomková Zuzana2Kilík Róbert3Sabo Ján4Department of Medical and Clinical Biophysics, Faculty of Medicine, University of P.J. Šafárik in Košice, Trieda SNP1, 04011Košice, SlovakiaDepartment of Medical and Clinical Biophysics, Faculty of Medicine, University of P.J. Šafárik in Košice, Trieda SNP1, 04011Košice, SlovakiaDepartment of Medical and Clinical Biophysics, Faculty of Medicine, University of P.J. Šafárik in Košice, Trieda SNP1, 04011Košice, Slovakia1st Department of Surgery, Faculty of Medicine, University of P.J. Šafárik in Košice, Trieda SNP1, 04011Košice, SlovakiaDepartment of Medical and Clinical Biophysics, Faculty of Medicine, University of P.J. Šafárik in Košice, Trieda SNP1, 04011Košice, SlovakiaTransforming RhoA proteins (RHOA) and their downstream Diaphanous homolog 1 proteins (DIAPH1) or mDia1 participate in the regulation of actin cytoskeleton which plays critical role in cells, i.e., morphologic changes and apoptosis.https://doi.org/10.1515/biol-2019-0070transforming rhoa proteindiaphanous homolog 1 proteinactin cytoskeletonstress fibre
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Bober Peter Alexovič Michal Tomková Zuzana Kilík Róbert Sabo Ján
spellingShingle	Bober Peter Alexovič Michal Tomková Zuzana Kilík Róbert Sabo Ján RHOA and mDia1 promotes apoptosis of breast cancer cells via a high dose of doxorubicin treatment Open Life Sciences transforming rhoa protein diaphanous homolog 1 protein actin cytoskeleton stress fibre
author_facet	Bober Peter Alexovič Michal Tomková Zuzana Kilík Róbert Sabo Ján
author_sort	Bober Peter
title	RHOA and mDia1 promotes apoptosis of breast cancer cells via a high dose of doxorubicin treatment
title_short	RHOA and mDia1 promotes apoptosis of breast cancer cells via a high dose of doxorubicin treatment
title_full	RHOA and mDia1 promotes apoptosis of breast cancer cells via a high dose of doxorubicin treatment
title_fullStr	RHOA and mDia1 promotes apoptosis of breast cancer cells via a high dose of doxorubicin treatment
title_full_unstemmed	RHOA and mDia1 promotes apoptosis of breast cancer cells via a high dose of doxorubicin treatment
title_sort	rhoa and mdia1 promotes apoptosis of breast cancer cells via a high dose of doxorubicin treatment
publisher	De Gruyter
series	Open Life Sciences
issn	2391-5412
publishDate	2019-12-01
description	Transforming RhoA proteins (RHOA) and their downstream Diaphanous homolog 1 proteins (DIAPH1) or mDia1 participate in the regulation of actin cytoskeleton which plays critical role in cells, i.e., morphologic changes and apoptosis.
topic	transforming rhoa protein diaphanous homolog 1 protein actin cytoskeleton stress fibre
url	https://doi.org/10.1515/biol-2019-0070
work_keys_str_mv	AT boberpeter rhoaandmdia1promotesapoptosisofbreastcancercellsviaahighdoseofdoxorubicintreatment AT alexovicmichal rhoaandmdia1promotesapoptosisofbreastcancercellsviaahighdoseofdoxorubicintreatment AT tomkovazuzana rhoaandmdia1promotesapoptosisofbreastcancercellsviaahighdoseofdoxorubicintreatment AT kilikrobert rhoaandmdia1promotesapoptosisofbreastcancercellsviaahighdoseofdoxorubicintreatment AT sabojan rhoaandmdia1promotesapoptosisofbreastcancercellsviaahighdoseofdoxorubicintreatment
_version_	1717785709511704576

RHOA and mDia1 promotes apoptosis of breast cancer cells via a high dose of doxorubicin treatment

Similar Items