Installation of -SO2F groups onto primary amides

Installation of -SO2F groups onto primary amides

A protocol of SO2F2-mediated installation of sulfonyl fluoride onto primary amides has been developed providing a new portal to sulfur(VI) fluoride exchange (SuFEx) click chemistry. The generated molecules contain pharmaceutically important amide and -SO2F moieties for application in the discovery o...

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Bibliographic Details
Main Authors: Jing Liu, Shi-Meng Wang, Njud S. Alharbi, Hua-Li Qin
Format: Article
Language:English
Published: Beilstein-Institut 2019-08-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
N-fluorosulfonyl amides
primary amides
sulfuryl fluoride (SO2F2)
Online Access:https://doi.org/10.3762/bjoc.15.186

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