Installation of -SO2F groups onto primary amides

A protocol of SO2F2-mediated installation of sulfonyl fluoride onto primary amides has been developed providing a new portal to sulfur(VI) fluoride exchange (SuFEx) click chemistry. The generated molecules contain pharmaceutically important amide and -SO2F moieties for application in the discovery o...

Full description

Bibliographic Details
Main Authors:	Jing Liu, Shi-Meng Wang, Njud S. Alharbi, Hua-Li Qin
Format:	Article
Language:	English
Published:	Beilstein-Institut 2019-08-01
Series:	Beilstein Journal of Organic Chemistry
Subjects:	N-fluorosulfonyl amides primary amides sulfuryl fluoride (SO2F2)
Online Access:	https://doi.org/10.3762/bjoc.15.186

id	doaj-2724d7c05703494bb8a1f7d5b0671910
record_format	Article
spelling	doaj-2724d7c05703494bb8a1f7d5b06719102021-02-02T02:22:30ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972019-08-011511907191210.3762/bjoc.15.1861860-5397-15-186Installation of -SO2F groups onto primary amidesJing Liu0Shi-Meng Wang1Njud S. Alharbi2Hua-Li Qin3State Key Laboratory of Silicate Materials for Architectures; School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan 430070, ChinaState Key Laboratory of Silicate Materials for Architectures; School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan 430070, ChinaBiotechnology Research group, Deportment of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi ArabiaState Key Laboratory of Silicate Materials for Architectures; School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan 430070, ChinaA protocol of SO2F2-mediated installation of sulfonyl fluoride onto primary amides has been developed providing a new portal to sulfur(VI) fluoride exchange (SuFEx) click chemistry. The generated molecules contain pharmaceutically important amide and -SO2F moieties for application in the discovery of new therapeutics.https://doi.org/10.3762/bjoc.15.186N-fluorosulfonyl amidesprimary amidessulfuryl fluoride (SO2F2)
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Jing Liu Shi-Meng Wang Njud S. Alharbi Hua-Li Qin
spellingShingle	Jing Liu Shi-Meng Wang Njud S. Alharbi Hua-Li Qin Installation of -SO2F groups onto primary amides Beilstein Journal of Organic Chemistry N-fluorosulfonyl amides primary amides sulfuryl fluoride (SO2F2)
author_facet	Jing Liu Shi-Meng Wang Njud S. Alharbi Hua-Li Qin
author_sort	Jing Liu
title	Installation of -SO2F groups onto primary amides
title_short	Installation of -SO2F groups onto primary amides
title_full	Installation of -SO2F groups onto primary amides
title_fullStr	Installation of -SO2F groups onto primary amides
title_full_unstemmed	Installation of -SO2F groups onto primary amides
title_sort	installation of -so2f groups onto primary amides
publisher	Beilstein-Institut
series	Beilstein Journal of Organic Chemistry
issn	1860-5397
publishDate	2019-08-01
description	A protocol of SO2F2-mediated installation of sulfonyl fluoride onto primary amides has been developed providing a new portal to sulfur(VI) fluoride exchange (SuFEx) click chemistry. The generated molecules contain pharmaceutically important amide and -SO2F moieties for application in the discovery of new therapeutics.
topic	N-fluorosulfonyl amides primary amides sulfuryl fluoride (SO2F2)
url	https://doi.org/10.3762/bjoc.15.186
work_keys_str_mv	AT jingliu installationofso2fgroupsontoprimaryamides AT shimengwang installationofso2fgroupsontoprimaryamides AT njudsalharbi installationofso2fgroupsontoprimaryamides AT hualiqin installationofso2fgroupsontoprimaryamides
_version_	1724309947038040064

Installation of -SO2F groups onto primary amides

Similar Items