Protective effect of NAC against malathion-induced oxidative stress in freshly isolated rat hepatocytes

Protective effect of NAC against malathion-induced oxidative stress in freshly isolated rat hepatocytes

Purpose: Induction of oxidative stress by Organophosphate compounds (OPs) has been previously reported. In the present work, the mechanism of protective effects of N-acetylcysteine as a glutathion (GSH) prodrug against malathion–induced cell toxicity was investigated. In this work, freshly isolated...

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Bibliographic Details
Main Authors: Sara Mostafalou, Mohammad Abdollahi, Mohammad Ali Eghbal, Nazli Saeedi Kouzehkonani
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2012-06-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Organophosphate Pesticides
Cytotoxicity
Oxidative Stress
Mitochondria
N-actylcycteine
Hepatocytes
Online Access:http://apb.tbzmed.ac.ir/Portals/0/Archive/Vol2No1/11.Eghbal.pdf

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