Boolean model of anchorage dependence and contact inhibition points to coordinated inhibition but semi-independent induction of proliferation and migration

Epithelial cells respond to their physical neighborhood with mechano-sensitive behaviors required for development and tissue maintenance. These include anchorage dependence, matrix stiffness-dependent proliferation, contact inhibition of proliferation and migration, and collective migration that bal...

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Bibliographic Details
Main Authors: Eric Guberman, Hikmet Sherief, Erzsébet Ravasz Regan
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
YAP
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037020303482