Circulating AIM Prevents Hepatocellular Carcinoma through Complement Activation

Circulating AIM Prevents Hepatocellular Carcinoma through Complement Activation

Summary: Hepatocellular carcinoma (HCC) is a widespread fatal disease and the third most common cause of cancer deaths. Here, we show the potent anti-HCC effect of the circulating protein AIM. As in adipocytes, AIM is incorporated into normal hepatocytes, where it interferes with lipid storage. In c...

Full description

Bibliographic Details
Main Authors: Natsumi Maehara, Satoko Arai, Mayumi Mori, Yoshihiro Iwamura, Jun Kurokawa, Toshihiro Kai, Shunsuke Kusunoki, Kaori Taniguchi, Kazutaka Ikeda, Osamu Ohara, Ken-ichi Yamamura, Toru Miyazaki
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714007347

Internet

http://www.sciencedirect.com/science/article/pii/S2211124714007347

Similar Items