Toll-like receptor ligands induce expression of the costimulatory molecule CD155 on antigen-presenting cells.

Toll-like receptor ligands induce expression of the costimulatory molecule CD155 on antigen-presenting cells.

Genotoxic stress and RAS induce the expression of CD155, a ligand for the immune receptors DNAM-1, CD96 and TIGIT. Here we show that antigen-presenting cells upregulate CD155 expression in response to Toll-like receptor activation. Induction of CD155 by Toll-like receptors depended on MYD88, TRIF an...

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Bibliographic Details
Main Authors: Neha Kamran, Yoshimi Takai, Jun Miyoshi, Subhra K Biswas, Justin S B Wong, Stephan Gasser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3547938?pdf=render

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http://europepmc.org/articles/PMC3547938?pdf=render

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