Chronic administration of fluoxetine and pro-inflammatory cytokine change in a rat model of depression.

This study evaluated the chronic effects of fluoxetine, a commonly prescribed SSRI antidepressant, on the peripheral and central levels of inflammatory cytokines including IL-1β, IL-6, TNF-α and IL-17 over a 4-interval in a rat model of chronic mild stress (CMS) which resembles the human experience...

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Bibliographic Details
Main Authors: Yanxia Lu, Cyrus S Ho, Xin Liu, Anna N Chua, Wei Wang, Roger S McIntyre, Roger C Ho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5648231?pdf=render