ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics

ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics

<p>Abstract</p> <p>Background</p> <p>Colorectal (CRC) carcinogenesis through various morphological stages has been linked to several genetic and epigenetic changes. The Raf/MEK/ERK (MAPK) signal transduction cascade is an important mediator of a number of cellular fates...

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Bibliographic Details
Main Authors:	Levidou Georgia, Saetta Angelica A, Gigelou Fanie, Karlou Maria, Papanastasiou Polyanthi, Stamatelli Angeliki, Kavantzas Nikolaos, Michalopoulos Nikolaos V, Agrogiannis George, Patsouris Efstratios, Korkolopoulou Penelope
Format:	Article
Language:	English
Published:	BMC 2012-02-01
Series:	World Journal of Surgical Oncology
Online Access:	http://www.wjso.com/content/10/1/47

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