Deletion of the Gene for the Type I Interferon Inhibitor I329L from the Attenuated African Swine Fever Virus OURT88/3 Strain Reduces Protection Induced in Pigs

Deletion of the Gene for the Type I Interferon Inhibitor I329L from the Attenuated African Swine Fever Virus OURT88/3 Strain Reduces Protection Induced in Pigs

Live attenuated vaccines are considered to be the fastest route to the development of a safe and efficacious African swine fever (ASF) vaccine. Infection with the naturally attenuated OURT88/3 strain induces protection against challenge with virulent isolates from the same or closely related genotyp...

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Bibliographic Details
Main Authors: Ana Luisa Reis, Lynnette C. Goatley, Tamara Jabbar, Elisabeth Lopez, Anusyah Rathakrishnan, Linda K. Dixon
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Vaccines
Subjects:
African swine fever virus
interferon
I329L
vaccine
Online Access:https://www.mdpi.com/2076-393X/8/2/262

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