Natural variation in life history and aging phenotypes is associated with mitochondrial DNA deletion frequency in <it>Caenorhabditis briggsae</it>

Natural variation in life history and aging phenotypes is associated with mitochondrial DNA deletion frequency in <it>Caenorhabditis briggsae</it>

<p>Abstract</p> <p>Background</p> <p>Mutations that impair mitochondrial functioning are associated with a variety of metabolic and age-related disorders. A barrier to rigorous tests of the role of mitochondrial dysfunction in aging processes has been the lack of model...

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Bibliographic Details
Main Authors: Smith Samson W, Knapp Jeremiah B, Martha Sarah R, de Haan Gene, Hicks Kiley A, Coleman-Hulbert Anna L, Estes Suzanne, Stein Kevin C, Denver Dee R
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/11/11

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