Synthesis of Flavone Derivatives via <i>N</i>-Amination and Evaluation of Their Anticancer Activities

Synthesis of Flavone Derivatives via <i>N</i>-Amination and Evaluation of Their Anticancer Activities

Seventeen new flavone derivatives substituted at the 4&#8242;-OH position were designed, synthesized and evaluated for their anticancer and antibacterial activities. Among them, compounds <b>3</b>, <b>4</b>, <b>6f</b>, <b>6e</b>, <b>6b</b&...

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Bibliographic Details
Main Authors: Ni Zhang, Jin Yang, Ke Li, Jun Luo, Su Yang, Jun-Rong Song, Chao Chen, Wei-Dong Pan
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Molecules
Subjects:
flavone
amino acid
anticancer activity
antiproliferation
Online Access:https://www.mdpi.com/1420-3049/24/15/2723

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