MiR-199a-3p/5p participated in TGF-β and EGF induced EMT by targeting DUSP5/MAP3K11 in pterygium

MiR-199a-3p/5p participated in TGF-β and EGF induced EMT by targeting DUSP5/MAP3K11 in pterygium

Abstract Background Recently, it has been reported that miRNA is involved in pterygium, however the exact underlying mechanism in pterygium is unrevealed and require further investigation. Methods The differential expression of miRNA in pterygium was profiled using microarray and validated with quan...

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Bibliographic Details
Main Authors: Siying He, Yifang Huang, Shiqi Dong, Chen Qiao, Guohua Yang, Shuai Zhang, Chen Wang, Yuting Xu, Fang Zheng, Ming Yan
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Journal of Translational Medicine
Subjects:
miR-199a
DUSP5
MAP3K11
Pterygium
EMT
Online Access:http://link.springer.com/article/10.1186/s12967-020-02499-2

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