Constitutive Expression of TERT Enhances β-Klotho Expression and Improves Age-Related Deterioration in Early Bovine Embryos

Constitutive Expression of TERT Enhances β-Klotho Expression and Improves Age-Related Deterioration in Early Bovine Embryos

Age-associated decline in oocyte quality is one of the dominant factors of low fertility. Aging alters several key processes, such as telomere lengthening, cell senescence, and cellular longevity of granulosa cells surrounding oocyte. To investigate the age-dependent molecular changes, we examined t...

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Bibliographic Details
Main Authors: Lianguang Xu, Muhammad Idrees, Myeong-Don Joo, Tabinda Sidrat, Yiran Wei, Seok-Hwan Song, Kyeong-Lim Lee, Il-Keun Kong
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
β-Klotho
FGFR1
TERT
cycloastragenol
bovine embryo
Online Access:https://www.mdpi.com/1422-0067/22/10/5327

Internet

https://www.mdpi.com/1422-0067/22/10/5327

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