How (specific) would like your T-cells today ?Generating T-cell therapeutic function through TCR-gene transfer

How (specific) would like your T-cells today ?Generating T-cell therapeutic function through TCR-gene transfer

T-cells are central players in the immune response against both pathogens and cancer. Their specificity is solely dictated by the T-cell receptor (TCR) they clonally express. As such, the genetic modification of T lymphocytes using pathogen- or cancer-specific T-cell receptors represents an appealin...

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Bibliographic Details
Main Authors: Inbal eDaniel-Meshulam, Shlomo eYa'acobi, Chen eAnkri, Cyrille J Cohen
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Immunology
Subjects:
Autoimmunity
Immunotherapy
infectious diseases
T-cells
T-cell receptor
TCR-gene transfer
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00186/full

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