A review on the efficacy and mechanism of action of Shenkang injection against chronic kidney disease

• Main Authors: Jun-Ju Zou, Xiao-Tao Zhou, Yan-Kun Chen, Jia-Lu Liu, Cheng Wang, Yue-Rong Ma, Li Wang
• Format: Article
• Language: English
• Published: Elsevier 2020-12-01
• Series: Biomedicine & Pharmacotherapy
• Subjects: Chronic kidney disease; Shenkang injection; Traditional Chinese medicine; Renal fibrosis
• Online Access: http://www.sciencedirect.com/science/article/pii/S075333222031026X

Chronic kidney disease (CKD) is one of the most common conditions which significantly increases the risk for serious health outcomes. Epidemiological investigations have shown that CKD has become a serious global health problem. At present, there are no treatments for CKD, thus the need for an effective and safe treatment for this condition. Shenkang Injection (SKI), which is an herbal medication in Chinese Medicine, has been used in the management and treatment of CKD and has achieved favorable therapeutic effects. The purpose of this paper is to review the clinical efficacy, mechanism of action, and safety profile of SKI when used in CKD, and to provide comprehensive potential evidence for its clinical application.