Integrin alpha-5 silencing leads to myofibroblastic differentiation in IPF-derived human lung fibroblasts
Background and objective: The term ‘fibroblast’ covers a heterogeneous cell population in idiopathic pulmonary fibrosis (IPF). The fibroblasts are considered as main effector cells, because they promote disease progression by releasing exaggerated amounts of extracellular matrix proteins and modifyi...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-06-01
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Series: | Therapeutic Advances in Chronic Disease |
Online Access: | https://doi.org/10.1177/2040622320936023 |