The Role of Proinflammatory Pathways in the Pathogenesis of Colitis-Associated Colorectal Cancer

Patients with inflammatory bowel disease (IBD) are at an increased risk of developing colorectal cancer (CRC). The risk factors of CRC in IBD patients include long disease duration, extensive colitis, severe histological inflammation, and coexistence with primary sclerosing cholangitis (PSC). Severa...

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Bibliographic Details
Main Authors: Chengxin Luo, Hu Zhang
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2017/5126048