P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE

P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE

Increased arterial stiffness occurs in older patients with peripheral arterial disease (PAD). In this study we compared arterial stiffness and central hemodynamic parameters in young (< 60 years of age) PAD patients and controls. In 31 PAD patients with an ankle-brachial index (ABI≤ 0.9) and...

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Main Authors: Mariella Catalano*, Giovanni Scandale, Gabriel Dimitrov, Marzio Minola, Martino Recchia, Francesca Galli, Gianni Carzaniga, Maria Carotta
Format: Article
Language:English
Published: Atlantis Press 2015-11-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125930603/view
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spelling doaj-26a1703cb0ba424dbb269fcd69ba0fde2020-11-25T03:27:57ZengAtlantis PressArtery Research 1876-44012015-11-011210.1016/j.artres.2015.10.261P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASEMariella Catalano*Giovanni ScandaleGabriel DimitrovMarzio MinolaMartino RecchiaFrancesca GalliGianni CarzanigaMaria CarottaIncreased arterial stiffness occurs in older patients with peripheral arterial disease (PAD). In this study we compared arterial stiffness and central hemodynamic parameters in young (< 60 years of age) PAD patients and controls. In 31 PAD patients with an ankle-brachial index (ABI≤ 0.9) and 42 controls, aortic Pulse wave velocity (aPWV), Augmentation index corrected for heart rate (AIx@75HR), aortic Pulse Pressure (aPP), Pulse Pressure Amplification (PPA), were measured using the SphygmoCor device. In young PAD patients aPWV and AIx@75HR were similar (p=0.10) (p=0.58) With respect to controls but aortic PP was higher (p=0.02) and the PP amplification ratio was lower (p=0.005). PAD in young subjects is associated with central hemodynamic alterations but not with degenerative stiffness of the large arteries.https://www.atlantis-press.com/article/125930603/view
collection DOAJ
language English
format Article
sources DOAJ
author Mariella Catalano*
Giovanni Scandale
Gabriel Dimitrov
Marzio Minola
Martino Recchia
Francesca Galli
Gianni Carzaniga
Maria Carotta
spellingShingle Mariella Catalano*
Giovanni Scandale
Gabriel Dimitrov
Marzio Minola
Martino Recchia
Francesca Galli
Gianni Carzaniga
Maria Carotta
P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE
Artery Research
author_facet Mariella Catalano*
Giovanni Scandale
Gabriel Dimitrov
Marzio Minola
Martino Recchia
Francesca Galli
Gianni Carzaniga
Maria Carotta
author_sort Mariella Catalano*
title P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE
title_short P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE
title_full P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE
title_fullStr P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE
title_full_unstemmed P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE
title_sort p4.17 arterial stiffness in young patients with peripheral arterial disease
publisher Atlantis Press
series Artery Research
issn 1876-4401
publishDate 2015-11-01
description Increased arterial stiffness occurs in older patients with peripheral arterial disease (PAD). In this study we compared arterial stiffness and central hemodynamic parameters in young (< 60 years of age) PAD patients and controls. In 31 PAD patients with an ankle-brachial index (ABI≤ 0.9) and 42 controls, aortic Pulse wave velocity (aPWV), Augmentation index corrected for heart rate (AIx@75HR), aortic Pulse Pressure (aPP), Pulse Pressure Amplification (PPA), were measured using the SphygmoCor device. In young PAD patients aPWV and AIx@75HR were similar (p=0.10) (p=0.58) With respect to controls but aortic PP was higher (p=0.02) and the PP amplification ratio was lower (p=0.005). PAD in young subjects is associated with central hemodynamic alterations but not with degenerative stiffness of the large arteries.
url https://www.atlantis-press.com/article/125930603/view
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