Integrated assessment of inflammatory process accompanying community-acquired pneumonia by means of radiometry

• Main Authors: Kondratjev A.S., Solodukhin K.A., Terekhov I.V., Parfenyuk V.K., Lifshits V.В., Arzhnikov V.V.
• Format: Article
• Language: Russian
• Published: Saratov State Medical University 2011-12-01
• Series: Саратовский научно-медицинский журнал
• Subjects: active radiometry; cytokines; inflammation; pneumonia
• Online Access: http://www.ssmj.ru/system/files/201104_817-822.pdf

The purpose of the article is to analyze possibility of active SHF radiometry use for inflammation monitoring in lower departments of lungs. Materials and methods: Analysis of humoral immunity (cytokine, complement and immunoglobu-lin status), angiogenesis, and modifications of extracellular matrix has been made by immune-enzyme method. Serum concentration of IL-1(3, IL-1Ra, TGF-(31, C3 and C5a components of complement system and lg M, lg G, VEGF-A, ММП-13 and TIMMP-2 has been estimated in the research. Intensity of radiation of lungs has been studied. Results: Synchronism of radiation dynamics with molecular markers has been determined. The period of changes of specified mediators is about 2 days. Critical time points of pathological process (3, 6, 8, 11 and 16 days) have been found out. Conclusions: It has been proved that SHF radiation of lungs may be applied in treatment of pneumonia for pathology monitoring