Lesion load may predict long-term cognitive dysfunction in multiple sclerosis patients.

Magnetic Resonance Imaging (MRI) techniques provided evidences into the understanding of cognitive impairment (CIm) in Multiple Sclerosis (MS).To investigate the role of white matter (WM) and gray matter (GM) in predicting long-term CIm in a cohort of MS patients.303 out of 597 patients participatin...

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Main Authors: Francesco Patti, Manuela De Stefano, Luigi Lavorgna, Silvia Messina, Clara Grazia Chisari, Domenico Ippolito, Roberta Lanzillo, Veria Vacchiano, Sabrina Realmuto, Paola Valentino, Gabriella Coniglio, Maria Buccafusca, Damiano Paolicelli, Alessandro D'Ambrosio, Patrizia Montella, Vincenzo Brescia Morra, Giovanni Savettieri, Bruno Alfano, Antonio Gallo, Isabella Simone, Rosa Viterbo, Mario Zappia, Simona Bonavita, Gioacchino Tedeschi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4376682?pdf=render