Stimulation of Suicidal Erythrocyte Death by the Antimalarial Drug Mefloquine

Stimulation of Suicidal Erythrocyte Death by the Antimalarial Drug Mefloquine

Background: The antimalarial drug mefloquine has previously been shown to stimulate apoptosis of nucleated cells. Similar to apoptosis, erythrocytes may enter suicidal death or eryptosis, which is characterized by cell shrinkage and phospholipid scrambling of the erythrocyte cell membrane with phosp...

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Bibliographic Details
Main Authors: Rosi Bissinger, Susanne Barking, Kousi Alzoubi, Guilai Liu, Guoxing Liu, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Cell volume
ROS
Phosphatidylserine
Calcium
Oxidative stress
Eryptosis
Malaria
Online Access:http://www.karger.com/Article/FullText/430305

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