Downregulation of ribosome biogenesis during early forebrain development

Downregulation of ribosome biogenesis during early forebrain development

Forebrain precursor cells are dynamic during early brain development, yet the underlying molecular changes remain elusive. We observed major differences in transcriptional signatures of precursor cells from mouse forebrain at embryonic days E8.5 vs. E10.5 (before vs. after neural tube closure). Gene...

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Bibliographic Details
Main Authors: Kevin F Chau, Morgan L Shannon, Ryann M Fame, Erin Fonseca, Hillary Mullan, Matthew B Johnson, Anoop K Sendamarai, Mark W Springel, Benoit Laurent, Maria K Lehtinen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-05-01
Series:eLife
Subjects:
forebrain
ribosome biogenesis
cerebrospinal fluid
amniotic fluid
MYC
Online Access:https://elifesciences.org/articles/36998

Internet

https://elifesciences.org/articles/36998

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