Effects of TRPA1 activation and inhibition on TRPA1 and CGRP expression in dorsal root ganglion neurons

Effects of TRPA1 activation and inhibition on TRPA1 and CGRP expression in dorsal root ganglion neurons

Transient receptor potential ankyrin 1 (TRPA1) is a key player in pain and neurogenic inflammation, and is localized in nociceptive primary sensory dorsal root ganglion (DRG) neurons. TRPA1 plays a major role in the transmission of nociceptive sensory signals. The generation of neurogenic inflammati...

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Bibliographic Details
Main Authors: Xiao-Lei Wang, Li-Wei Cui, Zhen Liu, Yue-Ming Gao, Sheng Wang, Hao Li, Hu-Xiang Liu, Ling-Jia Yu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; TRPA1; TRPV1; formaldehyde; menthol; CGRP; dorsal root ganglion; neuron; neurogenic inflammation; nociceptive signal; ERK1/2; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=1;spage=140;epage=148;aulast=Wang

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