Metachronous, Single Metastasis to the Parotid, from Primary Breast Cancer: A Case Report and Review of the Literature

Background. The parotid gland is an unusual site for metastatic disease and when metastasis occurs, it commonly originates from head and neck primaries. Spread from distant infraclavicular sites such as the breast, into the parotid, is even more unusual with very few cases reported in the literature...

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Main Authors: Michel Kmeid, François G. Kamar, Selim Nasser, Nabil Moukarzel
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2016/3965283
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spelling doaj-268f19dcc2e2454194fd0c69c7bbd7d02020-11-24T21:58:53ZengHindawi LimitedCase Reports in Oncological Medicine2090-67062090-67142016-01-01201610.1155/2016/39652833965283Metachronous, Single Metastasis to the Parotid, from Primary Breast Cancer: A Case Report and Review of the LiteratureMichel Kmeid0François G. Kamar1Selim Nasser2Nabil Moukarzel3School of Medicine, Lebanese University, Beirut, LebanonDepartment of Hematology-Oncology, Clemenceau Medical Center, Beirut, LebanonDepartment of Pathology, School of Medicine, Lebanese American University, Byblos, LebanonDepartment of Otolaryngology, Head and Neck Surgery, School of Medicine, Lebanese University, Beirut, LebanonBackground. The parotid gland is an unusual site for metastatic disease and when metastasis occurs, it commonly originates from head and neck primaries. Spread from distant infraclavicular sites such as the breast, into the parotid, is even more unusual with very few cases reported in the literature. Case Report. We describe the case of a 65-year-old woman presenting for a rapidly enlarging right parotid mass. She had a history of an invasive ductal carcinoma of the right breast and was disease-free in the past 6 years prior to her presentation. She was thereafter diagnosed as having a solitary parotid metastasis from breast origin. A total parotidectomy was done and she was referred for adjuvant radiotherapy. Conclusion. Any parotid metastasis should be investigated, especially in patients with a prior history of cancer where the possibility of metastasis, even if improbable, should be kept in mind. Fine needle aspiration biopsy (FNAB) is the first diagnostic procedure to be done and immunocytochemistry can provide valuable information even if it is not always needed for diagnosis. Superficial parotidectomy when feasible with adjuvant radiotherapy is the preferred approach for solitary metastasis of the parotid. The prognosis, however, remains poor regardless of the treatment modality used.http://dx.doi.org/10.1155/2016/3965283
collection DOAJ
language English
format Article
sources DOAJ
author Michel Kmeid
François G. Kamar
Selim Nasser
Nabil Moukarzel
spellingShingle Michel Kmeid
François G. Kamar
Selim Nasser
Nabil Moukarzel
Metachronous, Single Metastasis to the Parotid, from Primary Breast Cancer: A Case Report and Review of the Literature
Case Reports in Oncological Medicine
author_facet Michel Kmeid
François G. Kamar
Selim Nasser
Nabil Moukarzel
author_sort Michel Kmeid
title Metachronous, Single Metastasis to the Parotid, from Primary Breast Cancer: A Case Report and Review of the Literature
title_short Metachronous, Single Metastasis to the Parotid, from Primary Breast Cancer: A Case Report and Review of the Literature
title_full Metachronous, Single Metastasis to the Parotid, from Primary Breast Cancer: A Case Report and Review of the Literature
title_fullStr Metachronous, Single Metastasis to the Parotid, from Primary Breast Cancer: A Case Report and Review of the Literature
title_full_unstemmed Metachronous, Single Metastasis to the Parotid, from Primary Breast Cancer: A Case Report and Review of the Literature
title_sort metachronous, single metastasis to the parotid, from primary breast cancer: a case report and review of the literature
publisher Hindawi Limited
series Case Reports in Oncological Medicine
issn 2090-6706
2090-6714
publishDate 2016-01-01
description Background. The parotid gland is an unusual site for metastatic disease and when metastasis occurs, it commonly originates from head and neck primaries. Spread from distant infraclavicular sites such as the breast, into the parotid, is even more unusual with very few cases reported in the literature. Case Report. We describe the case of a 65-year-old woman presenting for a rapidly enlarging right parotid mass. She had a history of an invasive ductal carcinoma of the right breast and was disease-free in the past 6 years prior to her presentation. She was thereafter diagnosed as having a solitary parotid metastasis from breast origin. A total parotidectomy was done and she was referred for adjuvant radiotherapy. Conclusion. Any parotid metastasis should be investigated, especially in patients with a prior history of cancer where the possibility of metastasis, even if improbable, should be kept in mind. Fine needle aspiration biopsy (FNAB) is the first diagnostic procedure to be done and immunocytochemistry can provide valuable information even if it is not always needed for diagnosis. Superficial parotidectomy when feasible with adjuvant radiotherapy is the preferred approach for solitary metastasis of the parotid. The prognosis, however, remains poor regardless of the treatment modality used.
url http://dx.doi.org/10.1155/2016/3965283
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