Methylated Host Cell Gene Promoters and Human Papillomavirus Type 16 and 18 Predicting Cervical Lesions and Cancer.

Change in the host and/or human papillomavirus (HPV) DNA methylation profile is probably one of the main factors responsible for the malignant progression of cervical lesions to cancer. To investigate those changes we studied 173 cervical samples with different grades of cervical lesion, from normal...

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Bibliographic Details
Main Authors: Nina Milutin Gašperov, Ivan Sabol, Pavao Planinić, Goran Grubišić, Ivan Fistonić, Ante Ćorušić, Magdalena Grce
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4461273?pdf=render