Application of a BMP2-binding heparan sulphate to promote periodontal regeneration

Application of a BMP2-binding heparan sulphate to promote periodontal regeneration

Periodontitis is the most common inflammatory disease that leads to periodontal defects and tooth loss. Regeneration of alveolar bone and soft tissue in periodontal defects is highly desirable but remains challenging. A heparan sulphate variant (HS3) with enhanced affinity for bone morphogenetic pro...

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Bibliographic Details
Main Authors: BQ Le, JH Too, TC Tan, RAA Smith, V Nurcombe, SM Cool, N Yu
Format: Article
Language:English
Published: AO Research Institute Davos 2021-08-01
Series:European Cells & Materials
Subjects:
heparan sulphate
glycosaminoglycan
periodontal regeneration
bone tissue
alveolar bone
tooth
growth factor
bone morphogenetic protein-2.
Online Access:https://www.ecmjournal.org/papers/vol042/pdf/v042a09.pdf

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