Melatonin and alpha lipoic acid restore electrolytes and kidney morphology of lopinavir/ritonavir-treated rats

Melatonin and alpha lipoic acid restore electrolytes and kidney morphology of lopinavir/ritonavir-treated rats

Introduction: Lopinavir/ritonavir (LPV/r) may cause renal dysfunction such as electrolyte and acid base disorders and alteration in kidney morphology. Drug–induced renal dysfunction can occur through multiple mechanisms including oxidative stress and inflammation. Objectives: The current study...

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Bibliographic Details
Main Authors: Elias Adikwu, Nelson Brambaifa, Wolfe Atuboyedia Obianime
Format: Article
Language:English
Published: Society of Diabetic Nephropathy Prevention 2020-01-01
Series:Journal of Nephropharmacology
Subjects:
Lopinavir/ritonavir
Kidney
Toxicity
Antioxidants
Protection
Oxidative stress
Online Access:http://jnephropharmacology.com/PDF/npj-275

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