Variability of intensive care admission decisions for the very elderly.

Although increasing numbers of very elderly patients are requiring intensive care, few large sample studies have investigated ICU admission of very elderly patients. Data on pre triage by physicians from other specialities is limited. This observational cohort study aims at examining inter-hospital...

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Main Authors: Ariane Boumendil, Derek C Angus, Anne-Laure Guitonneau, Anne-Marie Menn, Christine Ginsburg, Khalil Takun, Alain Davido, Rafik Masmoudi, Benoît Doumenc, Dominique Pateron, Maité Garrouste-Orgeas, Dominique Somme, Tabassome Simon, Philippe Aegerter, Bertrand Guidet, ICE-CUB study group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3324496?pdf=render
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spelling doaj-262a4000628a421fad826c58ffeff2372020-11-24T22:14:35ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-0174e3438710.1371/journal.pone.0034387Variability of intensive care admission decisions for the very elderly.Ariane BoumendilDerek C AngusAnne-Laure GuitonneauAnne-Marie MennChristine GinsburgKhalil TakunAlain DavidoRafik MasmoudiBenoît DoumencDominique PateronMaité Garrouste-OrgeasDominique SommeTabassome SimonPhilippe AegerterBertrand GuidetICE-CUB study groupAlthough increasing numbers of very elderly patients are requiring intensive care, few large sample studies have investigated ICU admission of very elderly patients. Data on pre triage by physicians from other specialities is limited. This observational cohort study aims at examining inter-hospital variability of ICU admission rates and its association with patients' outcomes. All patients over 80 years possibly qualifying for ICU admission who presented to the emergency departments (ED) of 15 hospitals in the Paris (France) area during a one-year period were prospectively included in the study. Main outcome measures were ICU eligibility, as assessed by the ED and ICU physicians; in-hospital mortality; and vital and functional status 6 months after the ED visit. 2646 patients (median age 86; interquartile range 83-91) were included in the study. 94% of participants completed follow-up (n = 2495). 12.4% (n = 329) of participants were deemed eligible for ICU admission by ED physicians and intensivists. The overall in-hospital and 6-month mortality rates were respectively 27.2% (n = 717) and 50.7% (n = 1264). At six months, 57.5% (n = 1433) of patients had died or had a functional deterioration. Rates of patients deemed eligible for ICU admission ranged from 5.6% to 38.8% across the participating centers, and this variability persisted after adjustment for patients' characteristics. Despite this variability, we found no association between level of ICU eligibility and either in-hospital death or six-month death or functional deterioration. In France, the likelihood that a very elderly person will be admitted to an ICU varies widely from one hospital to another. Influence of intensive care admission on patients' outcome remains unclear.ClinicalTrials.gov NCT00912600.http://europepmc.org/articles/PMC3324496?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Ariane Boumendil
Derek C Angus
Anne-Laure Guitonneau
Anne-Marie Menn
Christine Ginsburg
Khalil Takun
Alain Davido
Rafik Masmoudi
Benoît Doumenc
Dominique Pateron
Maité Garrouste-Orgeas
Dominique Somme
Tabassome Simon
Philippe Aegerter
Bertrand Guidet
ICE-CUB study group
spellingShingle Ariane Boumendil
Derek C Angus
Anne-Laure Guitonneau
Anne-Marie Menn
Christine Ginsburg
Khalil Takun
Alain Davido
Rafik Masmoudi
Benoît Doumenc
Dominique Pateron
Maité Garrouste-Orgeas
Dominique Somme
Tabassome Simon
Philippe Aegerter
Bertrand Guidet
ICE-CUB study group
Variability of intensive care admission decisions for the very elderly.
PLoS ONE
author_facet Ariane Boumendil
Derek C Angus
Anne-Laure Guitonneau
Anne-Marie Menn
Christine Ginsburg
Khalil Takun
Alain Davido
Rafik Masmoudi
Benoît Doumenc
Dominique Pateron
Maité Garrouste-Orgeas
Dominique Somme
Tabassome Simon
Philippe Aegerter
Bertrand Guidet
ICE-CUB study group
author_sort Ariane Boumendil
title Variability of intensive care admission decisions for the very elderly.
title_short Variability of intensive care admission decisions for the very elderly.
title_full Variability of intensive care admission decisions for the very elderly.
title_fullStr Variability of intensive care admission decisions for the very elderly.
title_full_unstemmed Variability of intensive care admission decisions for the very elderly.
title_sort variability of intensive care admission decisions for the very elderly.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2012-01-01
description Although increasing numbers of very elderly patients are requiring intensive care, few large sample studies have investigated ICU admission of very elderly patients. Data on pre triage by physicians from other specialities is limited. This observational cohort study aims at examining inter-hospital variability of ICU admission rates and its association with patients' outcomes. All patients over 80 years possibly qualifying for ICU admission who presented to the emergency departments (ED) of 15 hospitals in the Paris (France) area during a one-year period were prospectively included in the study. Main outcome measures were ICU eligibility, as assessed by the ED and ICU physicians; in-hospital mortality; and vital and functional status 6 months after the ED visit. 2646 patients (median age 86; interquartile range 83-91) were included in the study. 94% of participants completed follow-up (n = 2495). 12.4% (n = 329) of participants were deemed eligible for ICU admission by ED physicians and intensivists. The overall in-hospital and 6-month mortality rates were respectively 27.2% (n = 717) and 50.7% (n = 1264). At six months, 57.5% (n = 1433) of patients had died or had a functional deterioration. Rates of patients deemed eligible for ICU admission ranged from 5.6% to 38.8% across the participating centers, and this variability persisted after adjustment for patients' characteristics. Despite this variability, we found no association between level of ICU eligibility and either in-hospital death or six-month death or functional deterioration. In France, the likelihood that a very elderly person will be admitted to an ICU varies widely from one hospital to another. Influence of intensive care admission on patients' outcome remains unclear.ClinicalTrials.gov NCT00912600.
url http://europepmc.org/articles/PMC3324496?pdf=render
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