Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex

Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex

Chronic hepatitis B is a major health problem worldwide, with more than 250 million chronic carriers. Hepatitis B virus interferes with the host innate immune system so as to evade elimination via almost all of its constituent proteins; nevertheless, the function of HBsAg with respect to immune esca...

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Bibliographic Details
Main Authors: Feiyan Deng, Gang Xu, Zhikui Cheng, Yu Huang, Caijiao Ma, Chuanjin Luo, Chen Yu, Jun Wang, Xiupeng Xu, Shi Liu, Ying Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
immune escape
hepatitis B surface antigen
TAK1-TAB2
phosphorylation
polyubiquitination
autophagic degradation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.618196/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.618196/full

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