Neuregulin 1 regulates amyloid precursor protein cell surface expression and non-amyloidogenic processing

Neuregulin 1 regulates amyloid precursor protein cell surface expression and non-amyloidogenic processing

The amyloid precursor protein (APP) is a key molecule in Alzheimer's disease. The prevailing view is that APP is initially transported to the plasma membrane as a full-length protein. Its localization at the cell surface can trigger downstream signaling and APP cleavage. Our previous work has s...

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Bibliographic Details
Main Authors:	Young-Jung Kim, Ji-Young Yoo, Ok-Soon Kim, Han-byeol Kim, Junghwa Ryu, Hye-Sun Kim, Jun-Ho Lee, Hong-Il Yoo, Dae-Yong Song, Tai-Kyoung Baik, Ran-Sook Woo
Format:	Article
Language:	English
Published:	Elsevier 2018-06-01
Series:	Journal of Pharmacological Sciences
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861318300859

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