The Neonatal and Juvenile Pig in Pediatric Drug Discovery and Development

The Neonatal and Juvenile Pig in Pediatric Drug Discovery and Development

Pharmacotherapy in pediatric patients is challenging in view of the maturation of organ systems and processes that affect pharmacokinetics and pharmacodynamics. Especially for the youngest age groups and for pediatric-only indications, neonatal and juvenile animal models can be useful to assess drug...

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Bibliographic Details
Main Authors: Miriam Ayuso, Laura Buyssens, Marina Stroe, Allan Valenzuela, Karel Allegaert, Anne Smits, Pieter Annaert, Antonius Mulder, Sebastien Carpentier, Chris Van Ginneken, Steven Van Cruchten
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceutics
Subjects:
pediatric pharmacology
juvenile pig model
translational research
drug discovery
drug development
drug safety
Online Access:https://www.mdpi.com/1999-4923/13/1/44

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