Linc-OIP5 in the breast cancer cells regulates angiogenesis of human umbilical vein endothelial cells through YAP1/Notch/NRP1 signaling circuit at a tumor microenvironment

Linc-OIP5 in the breast cancer cells regulates angiogenesis of human umbilical vein endothelial cells through YAP1/Notch/NRP1 signaling circuit at a tumor microenvironment

Abstract Background LincRNAs have been revealed to be tightly associated with various tumorigeneses and cancer development, but the roles of specific lincRNA on tumor-related angiogenesis was hardly studied. Here, we aimed to investigate whether linc-OIP5 in breast cancer cells affects the angiogene...

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Bibliographic Details
Main Authors: Qing Zhu, Jingchao Li, Qi Wu, Yongxia Cheng, Huizhe Zheng, Tao Zhan, Hongwei Wang, Yue Yang, Hongyan Wang, Ye Liu, Sufen Guo
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Biological Research
Subjects:
Tumor microenvironment
Angiogenesis
Linc-OIP5
Signal transduction
Breast cancer
HUVECs
Online Access:https://doi.org/10.1186/s40659-020-0273-0

Internet

https://doi.org/10.1186/s40659-020-0273-0

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